Citations of our research: 19,104
h-index: 47
i10-index 130
As of March, 2023
Year 2023
Suresh Awale,* Hayato Baba, Nguyen Duy Phan, Min Jo Kim, Juthamart Maneenet, Koichi Sawaki, Mitsuro Kanda, Tomoyuki Okumura, Tsutomu Fujii, Takuya Okada,* Takahiro Maruyama, Takahiro Okada, and Naoki Toyooka*
Targeting Pancreatic Cancer with Novel Plumbagin Derivatives: Design, Synthesis, Molecular Mechanism, In Vitro and In Vivo Evaluation
Journal of Medicinal Chemistry https://doi.org/10.1021/acs.jmedchem.3c00394
Targeting Pancreatic Cancer with Novel Plumbagin Derivatives: Design, Synthesis, Molecular Mechanism, In Vitro and In Vivo Evaluation
Journal of Medicinal Chemistry https://doi.org/10.1021/acs.jmedchem.3c00394
Kusawadee Plekratoke; Chantana Boonyarat; Orawan Monthakantirat; Natsajee Nualkaew; Jinda Wangboonskul; Suresh Awale; Yaowared Chulikhit; Supawadee Daodee; Charinya Khamphukdee; Suchada Chaiwiwatrakul , Pornthip Waiwut
The Effect of Ethanol Extract from Mesua ferrea Linn Flower on Alzheimer’s Disease and Its Underlying Mechanism
Curr. Issues Mol. Biol. 2023, 45(5), 4063-4079; https://doi.org/10.3390/cimb45050259
The Effect of Ethanol Extract from Mesua ferrea Linn Flower on Alzheimer’s Disease and Its Underlying Mechanism
Curr. Issues Mol. Biol. 2023, 45(5), 4063-4079; https://doi.org/10.3390/cimb45050259
Suresh Awale,* Michiko Jo, Shiro Watanabe, Naotoshi Shibahara, Kinzo Matsumoto
Uncovering the metabolomic effects of Kampo formulas using 1 H‐NMR spectroscopy: A case study of goreisan
Traditional & Kampo Medicine (First published: 14 April 2023)
https://doi.org/10.1002/tkm2.1369
Uncovering the metabolomic effects of Kampo formulas using 1 H‐NMR spectroscopy: A case study of goreisan
Traditional & Kampo Medicine (First published: 14 April 2023)
https://doi.org/10.1002/tkm2.1369
Nguyen Duy Phan, Ashraf M. Omar, Ikue Takahashi, Hayato Baba, Tomoyuki Okumura, Johji Imura, Takuya Okada, Naoki Toyooka, Tsutomu Fujii, Suresh Awale*
Nicolaioidesin C: An Antiausterity Agent Shows Promising Antitumor Activity in a Pancreatic Cancer Xenograft Mouse Model
Journal of Natural Products
https://doi.org/10.1021/acs.jnatprod.3c00019
Nicolaioidesin C: An Antiausterity Agent Shows Promising Antitumor Activity in a Pancreatic Cancer Xenograft Mouse Model
Journal of Natural Products
https://doi.org/10.1021/acs.jnatprod.3c00019
Shaimaa Fayez, Alessia Cacciatore, Juthamart Maneenet, Hung Hong Nguyen, Nasir Tajuddeen, Doris Feineis, Laurent Aké Assi, Suresh Awale,* Gerhard Bringmann*
Dioncophyllidine E: the first configurationally semi-stable, 7,3'-coupled naphthyldihydroisoquinoline alkaloid, from Ancistrocladus abbreviatus, with antiausterity activity against PANC-1 human pancreatic cancer cells
Bioorganic & Medicinal Chemistry Letters, 2023, 10 March 2023, 129234
https://doi.org/10.1016/j.bmcl.2023.129234
Dioncophyllidine E: the first configurationally semi-stable, 7,3'-coupled naphthyldihydroisoquinoline alkaloid, from Ancistrocladus abbreviatus, with antiausterity activity against PANC-1 human pancreatic cancer cells
Bioorganic & Medicinal Chemistry Letters, 2023, 10 March 2023, 129234
https://doi.org/10.1016/j.bmcl.2023.129234
Year 2022
Juthamart Maneenet, Ahmed M. Tawila, Ashraf M. Omar, Nguyen Duy Phan, Chiharu Ojima, Masahiro Kuroda, Mao Sato, Mio Mizoguchi, Ikue Takahashi and Suresh Awale*
Chemical Constituents of Callistemon subulatus and Their Anti-pancreatic Cancer Activity Against Human PANC-1 Cell Line
Plants, 2022, 11(19), 2466; https://doi.org/10.3390/plants11192466
Chemical Constituents of Callistemon subulatus and Their Anti-pancreatic Cancer Activity Against Human PANC-1 Cell Line
Plants, 2022, 11(19), 2466; https://doi.org/10.3390/plants11192466
Takuya Okada,* Yuri Chino, Keita Yokoyama, Yuki Fujihashi, Nguyễn Duy Phan, Juthamart Maneenet, Lanke Prudhvi,
Suresh Awale,* Naoki Toyooka
Design and synthesis of novel pipernonaline derivatives as anti-austerity agents against human pancreatic cancer PANC-1 cells
Bioorganic & Medicinal Chemistry, 2022, 71, 116963
https://doi.org/10.1016/j.bmc.2022.116963
Suresh Awale,* Naoki Toyooka
Design and synthesis of novel pipernonaline derivatives as anti-austerity agents against human pancreatic cancer PANC-1 cells
Bioorganic & Medicinal Chemistry, 2022, 71, 116963
https://doi.org/10.1016/j.bmc.2022.116963
Nguyen Ngoc Thanh Luan, Takuya Okada,* Ruka Arata, Lanke Prudhvi, Moe Miyaguchi, Yuri Kodama, Suresh Awale,* Naoki Toyooka
Structure-activity relationship study of 4′-O-methylgrynullarin derivatives for the development of novel anticancer agents based on anti-austerity strategy
Tetrahedron, 2022; 132931
https://doi.org/10.1016/j.tet.2022.132931
Structure-activity relationship study of 4′-O-methylgrynullarin derivatives for the development of novel anticancer agents based on anti-austerity strategy
Tetrahedron, 2022; 132931
https://doi.org/10.1016/j.tet.2022.132931
Daodee S, Monthakantirat O, Tantipongpiradet A, Maneenet J, Chotritthirong Y, Boonyarat C, Khamphukdee C, Kwankhao P, Pitiporn S, Awale S, Matsumoto K, Chulikhit Y.
Effect of Yakae-Prajamduen-Jamod Traditional Thai Remedy on Cognitive Impairment in an Ovariectomized Mouse Model and Its Mechanism of Action
Molecules. 2022; 27(13):4310.
https://doi.org/10.3390/molecules27134310
Effect of Yakae-Prajamduen-Jamod Traditional Thai Remedy on Cognitive Impairment in an Ovariectomized Mouse Model and Its Mechanism of Action
Molecules. 2022; 27(13):4310.
https://doi.org/10.3390/molecules27134310
Ahmed M. Tawila, Ashraf M. Omar, Nguyen Duy Phan, Ikue Takahashi, Juthamart Maneenet and Suresh Awale*
Callistrilone epimers from Callistemon citrinus and their antiausterity activity against the PANC-1 human pancreatic cancer cell line
Tetrahedron Letters, May 2022, 153881
DOI:https://doi.org/10.1016/j.tetlet.2022.153881
Callistrilone epimers from Callistemon citrinus and their antiausterity activity against the PANC-1 human pancreatic cancer cell line
Tetrahedron Letters, May 2022, 153881
DOI:https://doi.org/10.1016/j.tetlet.2022.153881
Takuya Okada, Nguyen Ngoc Thanh Luan, Ruka Arata, Suresh Awale, Naoki Toyooka
Total Synthesis of 4'-O-Methylgrynullarin and Related Isoflavone Natural Products
ChemistrySelect, 2022, 7, e202201136 DOI: 10.1002/slct.202201136
Total Synthesis of 4'-O-Methylgrynullarin and Related Isoflavone Natural Products
ChemistrySelect, 2022, 7, e202201136 DOI: 10.1002/slct.202201136
Nguyen Duy Phan, Ashraf M. Omar, Sijia Sun, Juthamart Maneenet, Dya Fita Dibwe, Mao Sato, Surya Kant Kalauni, Naoki Toyooka, Tsutomu Fujii, Suresh Awale*
Abietane diterpenes from Abies spectabilis and their Anti-pancreatic Cancer Activity against the MIA PaCa-2 Cell Line
Bioorganic & Medicinal Chemistry Letters, 2022, 66, 128723
https://doi.org/10.1016/j.bmcl.2022.128723
Abietane diterpenes from Abies spectabilis and their Anti-pancreatic Cancer Activity against the MIA PaCa-2 Cell Line
Bioorganic & Medicinal Chemistry Letters, 2022, 66, 128723
https://doi.org/10.1016/j.bmcl.2022.128723
Aki Kohyama, MinJo Kim, Rei Yokoyama, Sijia Sun, Ashraf M. Omar, Nguyen Duy Phan, Meselhy R. Meselhy, Kiyoshi Tsuge,
Suresh Awale,* Yuji Matsuya*
Structure-Activity Relationship and Mechanistic Study on Guggulsterone derivatives; Discovery of New Anti-pancreatic Cancer Candidate
Bioorganic & Medicinal Chemistry,
Volume 54, 15 January 2022, 116563 DOI:10.1016/j.bmc.2021.116563
Suresh Awale,* Yuji Matsuya*
Structure-Activity Relationship and Mechanistic Study on Guggulsterone derivatives; Discovery of New Anti-pancreatic Cancer Candidate
Bioorganic & Medicinal Chemistry,
Volume 54, 15 January 2022, 116563 DOI:10.1016/j.bmc.2021.116563
Year 2021
Sijia Sun, Min Jo Kim, Ashraf M. Omar, Nguyen Duy Phan, Suresh Awale*
(+)-Panduratin A induces PANC-1 human pancreatic cancer cell death preferentially under nutrient starvation by inhibiting PI3K/Akt/mTOR/autophagy signaling pathway
Phytomedicine Plus, DOI:10.1016/j.phyplu.2021.100101
(+)-Panduratin A induces PANC-1 human pancreatic cancer cell death preferentially under nutrient starvation by inhibiting PI3K/Akt/mTOR/autophagy signaling pathway
Phytomedicine Plus, DOI:10.1016/j.phyplu.2021.100101
- Juthamart Maneenet , Orawan Monthakantirat , Supawadee Daodee, Chantana Boonyarat, Yutthana Chotritthirong, Pakakrong Kwankhao, Supaporn Pitiporn, Suresh Awale and Yaowared Chulikhit
Merging the Multi-Target Effects of Kleeb Bua Daeng, a Thai Traditional Herbal Formula in Unpredictable Chronic Mild Stress-Induced DepressionMerging the Multi-Target Effects of Kleeb Bua Daeng, a Thai Traditional Herbal Formula in Unpredictable Chronic Mild Stress-Induced Depression
Pharmaceuticals 2021, 14(7), 659; https://doi.org/10.3390/ph14070659
- Sijia Sun, Min Jo Kim, Ashraf M. Omar, Nguyen Duy Phan, Mio Aoike, and Suresh Awale*
GDP induces PANC-1 human pancreatic cancer cell death preferentially under nutrient starvation by inhibiting PI3K/Akt/mTOR/autophagy signaling pathway
Chemistry and Biodiversity, 2021, In Press, DOI: 10.1002/cbdv.202100389
- Ashraf M. Omar, Sijia Sun, Min Jo Kim, Nguyen Duy Phan, Ahmed M. Tawila, and Suresh Awale*
Benzophenones from Betula alnoides with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line
Journal of Natural Products
Publication Date:May 19, 2021
https://doi.org/10.1021/acs.jnatprod.1c00150
- Juthamart Maneenet, Ashraf M. Omar, Sijia Sun, Min Jo Kim, Supawadee Daodee, Orawon Monthakantirat, Chantana Boonyarat, Yaowared Chulikhit* and Suresh Awale*
Benzylisoquinoline alkaloids from Nelumbo nucifera Gaertn. petals with antiausterity activities against the HeLa human cervical cancer cell line
https://doi.org/10.1515/znc-2020-0304
Zeitschrift für Naturforschung C 2021, Volume 76, Issue: 11-12: In Press
- Sijia Sun, Ashraf M. Omar, Min Jo Kim, Nguyen Duy Phan, Yaowared Chulikhit, Suresh Awale.*
Chemical Constituents of Thai Piper ribesoides and Their Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line.
Fitoterapia
Volume 151, June 2021, 104901
DOI: https://doi.org/10.1016/j.fitote.2021.104901
- Sijia Sun, Dya Fita Dibwe, Min Jo Kim, Ashraf M.Omar, Nguyen Duy Phan, Haruk Fujino, Nusrin Pongterdsak, Kritsaya Chaithatwatthana, Ampai Phrutivorapongkul, SureshAwale*
A new anti-austerity agent, 4′-O-methylgrynullarin from Derris scandens induces PANC-1 human pancreatic cancer cell death under nutrition starvation via inhibition of Akt/mTOR pathway
Bioorganic & Medicinal Chemistry Letters
Volume 40, 15 May 2021, 127967
DOI: https://doi.org/10.1016/j.bmcl.2021.127967
- Sijia Sun, Min Jo Kim, Dya Fita Dibwe, Ashraf M. Omar, Sirivan Athikomkulchai, Ampai Phrutivorapongkul, Takuya Okada, Kiyoshi Tsuge, Naoki Toyooka, Suresh Awale*
Anti-Austerity Activity of Thai Medicinal Plants: Chemical Constituents and Anti-Pancreatic Cancer Activities of Kaempferia parviflora
Plants 2021, 10(2), 229
DOI: https://doi.org/10.3390/plants10020229
- Mai T. T. Nguyen, Hai X. Nguyen, Phu H. Dang, Tho H. Le, Truong N. V. Do, Ashraf M. Omar, Suresh Awale, Nhan T. Nguyen
Panduratins Q–Y, dimeric metabolites from Boesenbergia rotunda and their antiausterity activities against the PANC‑1 human pancreatic cancer cell line
Phytochemistry Volume 183, March 2021, 11264
DOI: https://doi.org/10.1016/j.phytochem.2020.112646
- Shaimaa Fayez, Alessia Cacciatore, Sijia Sun, Minjo Kim, Laurent Aké Assi, Doris Feineis, Suresh Awale,* Gerhard Bringmann*
Ancistrobrevidines A-C and Related 5,1'-Coupled Naphthylisoquinoline Alkaloids with Cytotoxic Activities against HeLa and Pancreatic Cancer Cells, from the West African Liana Ancistrocladus abbreviatus
Bioorganic & Medicinal Chemistry Volume 30, 15 January 2021, 115950
DOI: https://doi.org/10.1016/j.bmc.2020.115950
- Umeyama L, Hardianti B, Kasahara S, Dibwe DF, Awale S, Yokoyama S, Hayakawa Y.
Anti-inflammatory effects of Morus alba Linne bark on the activation of toll-like receptors and imiquimod-induced ear edema in mice.
BMC Complement Med Ther. 21:115. (2021) .
Year 2020
- Ashraf M.Omar, Sijia Sun, Min Jo Kim, Ahmed M Tawila, Dya Fita Dibwe, Ampai Phrutivorapongkul, Naoki Toyooka, Suresh Awale*
Highly oxygenated spiro-biflavanoids from Anneslea fragrans twigs
Phytochemistry Letters, 2020, 40, 21-25.
DOI: https://doi.org/10.1016/j.phytol.2020.09.005
- Ahmed M. Tawila, Sijia Sun, Min Jo Kim, Ashraf M. Omar, Dya Fita Dibwe, Suresh Awale*
A triterpene lactone from Callistemon citrinus inhibits the PANC-1 human pancreatic cancer cells viability via suppression of unfolded protein response
Chemistry and Biodiversity, 2020, 17, e2000495. DOI:10.1002/cbdv.202000495
- Hung‐Chiuan Chen, Suresh Awale, Chean‐Ping Wu, Hu‐Hui Lee, Hsi‐Tien Wu
Co‐cultured bone marrow mesenchymal stem cells repair thioacetamide‐induced hepatocyte damage
Cell Biology International, 2020, 1-14: https://doi.org/10.1002/cbin.11453
- Phu H. Dang, Thien H. X. Dao, Vien T. Le, Chien M. Nguyen, Tin T. Ly, Hai X. Nguyen, Tho H. Le, Truong N. V. Do, Mai T. T. Nguyen, Sijia Sun, Suresh Awale, Nhan T. Nguyen
Synthesis of Alkyl Triphenylphosphonium Ostruthin Derivatives as Potential Cytotoxic Candidates
ChemistrySelect, 2020, DOI:10.1002/slct.202003152
- Mai Thanh Thi Nguyen, Hai Xuan Nguyen, Tho Huu Le, Truong Nhat Van Do, Phu Hoang Dang, Tung Van Pham, Truc Thanh Minh Giang, Sijia Sun, Min Jo Kim, Ahmed M. Tawila, Ashraf M. Omar, Suresh Awale & Nhan Trung Nguyen.
A new flavanone derivative from the rhizomes of Boesenbergia pandurata
Natural Product Research, 2020, DOI: 10.1080/14786419.2020.1837822
- Dinh Xuan Doan, Sijia Sun, Ashraf M. Omar, Dong T. Nguyen, Anh L. T. Hoang, Hironori Fujiwara, Kinzo Matsumoto, Hang T. N. Pham, Suresh Awale
Chemical constituents and absolute configuration of megastigmanes’ isolated from Sedum sarmentosum Bunge
Natural Product Research: 2020, DOI: 10.1080/14786419.2020.1834549
- Moustafa Fathy, Sijia Sun, Qing-Li Zhao Mohamed Abdel-Aziz, Gamal E. A. Abuo-Rahma, Suresh Awale, Toshio Nikaido
A new ciprofloxacin-derivative inhibits proliferation and suppresses migration ability of HeLa cells
Anticancer Research, 2020, 40, 5025-5033. DOI: 10.21873/anticanres.14505
- Ahmed M. Tawila, Sijia Sun, Min Jo Kim, Ashraf M. Omar, Dya Fita Dibwe , Jun-ya Ueda, Naoki Toyooka, Suresh Awale*
Highly Potent Antiausterity Agents from Callistemon citrinus and Their Mechanism of Action against the PANC-1 Human Pancreatic Cancer Cell Line
Journal of Natural Products 2020, 83, 2221-2232. DOI:10.1021/acs.jnatprod.0c00330
- Ahmed M. Tawila, Sijia Sun, Min Jo Kim, Ashraf M. Omar, Dya Fita Dibwe , Jun-ya Ueda, Naoki Toyooka, Suresh Awale*
Chemical constituents of Callistemon citrinus from Egypt and their antiausterity activity against PANC-1 pancreatic cell line
Bioorganic & Medicinal Chemistry Letters, Volume 30, Issue 16, 15 August 2020, 127352 DOI:10.1016/j.bmcl.2020.127352
- Ashraf M.Omar, Sijia Sun, Min Jo Kim, Ahmed M Tawila, Dya Fita Dibwe, Ampai Phrutivorapongkul, Naoki Toyooka, Suresh Awale*
Fragranol A: A new class of spiro-triflavanoid hybrid with an unprecedented carbon skeleton from Anneslea fragrans
Tetrahedron Letters, 2020, 29, 152099. https://doi.org/10.1016/j.tetlet.2020.152099
- Nithya Balakrishnan, Jebiti Haribabu, Anantha Krishnan Dhanabalan, Srividya Swaminathan, Sijia Sun, Dya Fita Dibwe, Nattamai Bhuvanesh, Suresh Awale, R. Karvembu
Thiosemicarbazone(s)-anchored water soluble mono- and bimetallic Cu(II) complexes: Enzymes-like activities, biomolecular interactions, anticancer property and real-time live cytotoxicity
Dalton Transactions 2020, 49, 9411-9424. https://doi.org/10.1039/D0DT01309A
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- Mai T. T. Nguyen, Khang D. H. Nguyen, Phu H. Dang, Hai X. Nguyen, Suresh Awale, Nhan T. Nguyen
A new cytotoxic cardenolide from the roots of Calotropis gigantea
Natural Product Research, 2020, Jun 22, 1-6
DOI: https://doi.org/10.1080/14786419.2020.1781114 .
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- Omar A.M., Dibwe D.F., Sun S., Tawila A.M., Kim M.J., Phrutivorapongkul A., Toyooka N., Awale S.*
Fragranone C: A New Dihydrochalcone Glucopyranoside from Anneslea fragrans twigs
Natural Product Research Apr 2:1-6. doi: 10.1080/14786419.2020 (In Press)
- Alilou M., Dibwe D.F., Schwaiger S., Khodami M., Troppmair J. Awale S.,* Stuppner H.
Antiausterity Activity of Secondary Metabolites from the Roots of Ferula hezarlalehzaricaagainst the PANC-1 Human Pancreatic Cancer Cell Line
Journal of Natural Products 2020, 83, 1099-1106.
https://doi.org/10.1021/acs.jnatprod.9b01109
- Shaimaa Fayez S., Bruhn T., Feineis D., Assi L. A., Awale S.* Bringmann G.*
Ancistrosecolines A–F, Unprecedented seco-Naphthylisoquinoline Alkaloids from the Roots of Ancistrocladus abbreviatus, with Apoptosis-Inducing Potential against HeLa Cancer Cells
Journal of Natural Products 2020, 83, 1139-1151.
https://doi.org/10.1021/acs.jnatprod.9b01168
- Mai T. T. Nguyen, Khang, D. H. Nguyen, Phu H. Dang, Hai X. Nguyen, Suresh Awale* Nhan T. Nguyen*
Calosides A–F, Cardenolides from Calotropis gigantea and Their Cytotoxic Activity
Journal of Natural Products 2020, 83, 385-391.
https://doi.org/10.1021/acs.jnatprod.9b00875
- Aki Kohyama, Rei Yokoyama, Dya Fita Dibwe, SaharEl-Mekkawy, Meselhy R. Meselhy, Suresh Awale,* Yuji Matsuya*
Synthesis of guggulsterone derivatives as potential anti-austerity agents against PANC-1 human pancreatic cancer cells
Bioorg. Med. Chem. Lett. 2020, 30,126964.
https://doi.org/10.1016/j.bmcl.2020.126964
- Benjamin E. Alexander, Sijia Sun, Matthew J. Palframan, Gabriele Kociok-Köhn, Dya Fita Dibwe, Shiro Watanabe, Lorenzo Caggiano, Suresh Awale,* Simon E. Lewis*
Sidechain diversification of grandifloracin allows identification of analogues with enhanced anti-austerity activity against human PANC-1 pancreatic cancer cells
ChemMedChem 2020, 15, 125-135
DOI: 10.1002/cmdc.201900549
Year 2019
- Juthamart Maneenet, Supawadee Daodee, Orawan Monthakantirat, Chantana Boonyarat, Charinya Khamphukdee, Pakakrong Kwankhao, Supaporn Pitiporn, Suresh Awale, Yaowared Chulikhit, and Anake Kijjoa
Kleeb Bua Daeng, a Thai Traditional Herbal Formula, Ameliorated Unpredictable Chronic Mild Stress-Induced Cognitive Impairment in ICR Mice
Molecules 2019, 24(24), 4587; https://doi.org/10.3390/molecules24244587
- Ashraf M. Omar, Dya Fita Dibwe, Ahmed M. Tawila, Sijia Sun, Min Jo Kim, Suresh Awale*
Chemical constituents from Artemisia vulgaris and their antiausterity activities against the PANC-1 human pancreatic cancer cell line
Natural Product Research.
DOI: https://doi.org/10.1080/14786419.2019.1700246
- Ashraf M. Omar, Dya Fita Dibwe, Ahmed M. Tawila, Sijia Sun, Ampai Phrutivorapongkul, Suresh Awale*
Chemical Constituents of Anneslea fragransand Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line
J. Nat. Prod. 2019, 82, 3133-3139.
DOI: https://doi.org/10.1021/acs.jnatprod.9b00735
- Dieudonné Tshitenge Tshitenge, Torsten Bruhn, Doris Feineis, David Schmidt, Virima Mudogo, Marcel Kaiser, Reto Brun, Frank Würthner, Suresh Awale*, Gerhard Bringmann*
Ealamines A–H, a Series of Naphthylisoquinolines with the Rare 7,8′-Coupling Site, from the Congolese Liana Ancistrocladus ealaensis, Targeting Pancreatic Cancer Cells
J. Nat. Prod. 2019, 82, 3150-3164.
https://doi.org/10.1021/acs.jnatprod.9b00755
ACS Editors' Choice for new research of importance to the global scientific community
- Awale S.*, Okada T., Dibwe D.F., Maruyama T., Takahara S., Okada T., Endo S., Toyooka N.*
Design and synthesis of functionalized coumarins as potential anti-austerity agents that eliminates cancer cells' tolerance to nutrition starvation
Bioorg. Med. Chem. Lett. 2019, 29,1779-1784
DOI: https://doi.org/10.1016/j.bmcl.2019.05.010
- Qingyun Guo, Ken Ebihara, Hironori Fujiwara, Kazufumi Toume, Suresh Awale, Ryota Araki, Takeshi Yabe, Erbo Dong, Kinzo Matsumoto
Kami-shoyo-san ameliorates sociability deficits in ovariectomized mice, a putative female model of autism spectrum disorder, via facilitating dopamine D1 and GABAA receptor function
Journal of Ethnopharmacology
- Guo Q.-Y., Ebihara K., Shimodaira T., Fujiwara H., Toume K., Dibwe D.F., Awale S., Araki R., Yabe T., Matsumoto K.:
Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism.
PLoS One.14(1):e0211266, 2019.
DOI: 10.1371/journal.pone.0211266. eCollection 2019. - Jeyalakshmi K., Haribabu J., Balachandran C., Narmatha E., Bhuvanesh N.S.P., Aoki S., Awale S., Karvembu R.
Highly active copper(I) complexes of aroylthiourea ligands against cancer cells – synthetic and biological studies
New J. Chem.43: 3188, 2019. DOI: 10.1039/c8nj04246b.
- Fujiwara H., Yoshida J, Dibwe D.F., Awale S, Hoshino H., Kohama H., Arai H., Kudo Y., Matsumoto K.
Orengedokuto and san'oshashinto improve memory deficits by inhibiting aging-dependent activation of glycogen synthase kinase-3β
Journal of Traditional and Complementary Medicine
DOI: 10.1016/j.jtcme.2018.12.001
Year 2018
- Fayez S. Li J., Feineis D., Assi L.K., Kaiser M., Brun R., Awale S., Bringmann G.*
Ancistrobrevines E-J and related naphthylisoquinoline alkaloids from the West African liana Ancistrocladus abbreviatus with inhibitory activities against Plasmodium falciparum and PANC-1 human pancreatic cancer cells
Fitoterapia, 2018, 131, 245-259.
DOI: 10.1016/j.fitote.2018.11.006
- Awale S.,* Dibwe D. F., Balachandran C., Fayez S. Li J., Feineis D., Lombe B.K. Bringmann G.*
Ancistrolikokine E3, a 5,8-Coupled Naphthylisoquinoline Alkaloid, Eliminates the Tolerance of Cancer Cells to Nutrition Starvation by Inhibition of the Akt/mTOR/Autophagy Signaling Pathway
J. Nat. Prod., 2018, 81, 2282-2291.
DOI: 10.1021/acs.jnatprod.8b00733
- Sun S., Phrutivorapongkul A., Dibwe D. F., Balachandran C., Awale S.*
Chemical constituents of Thai Citrus hystrix and their antiausterity activity against the PANC-1 human pancreatic cancer cell line.
J. Nat. Prod., 2018, 81, 1877-1883.
- Muyisa S., Lombe B.K., Feineis D., Dibwe D.F., Maharaj V., Awale S.,* Bringmann G.*
Ancistroyafungines A-D, 5,8′- and 5,1′-coupled naphthylisoquinoline alkaloids from a Congolese Ancistrocladus species, with antiausterity activities against human PANC-1 pancreatic cancer cells
Fitoterapia, 2018, 130, 6-16.
- スレス アワレ
留学生としての人生と日本の大学の教員への旅 ―その中で感じた日本
ファルマシア 54 巻 (2018) 5 号 p. 455
- Do T.N.V., Nguyen H.X., Le T.H., Ngo T.M.T., Dang P.H., Phung N.H., Vo N.T., Nguyen D.M., Le N.H.T., Le T.T., Nguyen M.T.T, Awale S., Nguyen N.T.
A New Compound from the Rhizomes of Boesenbergia pandurata
Natural Products Communication, 13, 739-740, 2018.
- Balachandran C., Haribabu J., Jeyalakshmi K., Bhuvanesh N.S.P., Karvembu R., Emi N, Awale S.
Nickel(II) bis(isatinthiosemicarbazone) complexes induced apoptosis through mitochondrial signaling pathway and G0/G1 cell cycle arrest in IM-9 cells
Journal of Inorganic Biochemistry, 182, 208-221, 2018.
- Thirunavukkarasu T., Sparkes H.A., Balchandran C., Awale S., Natarajan K.
Bis( μ-chloro) bridged 1D CuI and CuII coordination polymer complex and mononuclear CuII complex: Synthesis, crystal structure and biological properties
J. Photochem. Photobiol. B: Biology, 181, 59-69, 2018
DOI: 10.1016/j.jphotobiol.2018.02.013
- Lombe B.K., Feineis D., Mudogo V., Brun R., Awale S,* Bringmann G.*
Michellamines A6 and A7, and further mono- and dimeric naphthylisoquinoline alkaloids from a Congolese Ancistrocladus liana and their antiausterity activities against pancreatic cancer cells
RSC Advances, 8, 5243-525 (2018).
DOI: 10.1039/C8RA00363G
- Nguyen H.X. , Do T.N.V., Nguyen N.T.T., Dang P.H., Tho L.H., Awale S.*, Nguyen N.T.T.*
A New Alkenylphenol from The Propolis of Stingless Bee Trigona minor
Natural Products Communication, 13, 69-70 (2018).
- Mahendran P., Rajendran A J., Balchandran C. Stalin A, Saravanan Rangan, Loganathan Kothandapani, Chennakesava Rao Kella, S. Awale, Hiteshkumar B.N.
Synthesis of novel β-amino alcohols from phenylacetylcarbinol - cytotoxicity activity against A549 cells and molecular docking.
Res. Chem. Intermediat. 44, 535-552 (2018)
DOI: 10.1007/s11164-017-3118-x
- Fujiwara H., Tsushima R., Okada R., Awale S., Araki R., Yabe T., Matsumoto K.
Sansoninto, a traditional herbal medicine, ameliorates behavioral abnormalities and down-regulation of early growth response-1 expression in mice exposed to social isolation stress
J. Trad. Complement. Med. 8 (1 ), 81-88 (2018).
DOI: 10.1016/j.jtcme.2017.03.004
Year 2017
- Fayez S. Li J., Feineis D., Mudogo V., Awale S.*, Bringmann G.*
Ancistrolikokines E-H and Related 5,8'-coupled Naphthylisoquinoline alkaloids from the Congolese Liana Ancistrocladus likoko with Antiausterity Activities against PANC-1 Human Pancreatic Cancer Cells
RSC Advances, 7, 53740-53751 (2017).
- Li J., Seupel R., Bruhn T., Feineis D., Kaiser M., Brun R., Mudogo V., Awale S.*, Bringmann G.*
Jozilebomines A and B, Naphthylisoquinoline Dimers from the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line
J. Nat. Prod., 80, 2087-2817 (2017).
DOI: 10.1021/acs.jnatprod.7b00650
- Dibwe D.F., Sun S., Ueda J., Balachandran C., Matsumoto K., Awale S.*
Discovery of potential antiausterity agents from the Japanese Cypress Chamaecyparis obtusa
Bioorg. Med. Chem. Lett. 27, 4898–4903 (2017).
DOI:https://doi.org/10.1016/j.bmcl.2017.09.034
- Nguyen H.X. Nguyen M.T.T., Nguyen N.T., Awale S.*
Chemical Constituents of Propolis from Vietnamese Trigona minor and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Lin
J. Nat. Prod. 80, 2345-2352 (2017).
DOI:10.1021/acs.jnatprod.7b00375
- Fathy M., Awale S., Nikaido T.
Phosphorylated Akt Protein at Ser473 Enables HeLa Cells to Tolerate Nutrient-Deprived Conditions
Asian Pac. J. Cancer Prev . 18, 3255-3260 (2017).
DOI:10.22034/APJCP.2017.18.12.3255
- Ebihara K., Fujiwara H., Awale S, Dibwe D.F., Araki R., Yabe T., Matsumto K.
Decrease in endogenous brain allopregnanolone induces autism spectrum disorder (ASD)-like behavior in mice: a novel animal model of ASD
Behavioural Brain Research I334, 6-15 (2017).
DOI: 10.1016/j.bbr.2017.07.019
- Dieudonné Tshitenge Tshitenge, Doris Feineis, Suresh Awale, Gerhard Bringmann
Gardenifolins A–H, Scalemic Neolignans from Gardenia ternifolia: Chiral Resolution, Configurational Assignment, and Cytotoxic Activities against the HeLa Cancer Cell Line
J. Nat. Prod., 80, 1604-1614 (2017).
DOI: 10.1021/acs.jnatprod.7b00180
- Chang H., Wang Y., Gao X., Song Z., Awale S., Han N., Liu Z., Yin J.
Lignans from the root of Wikstroemia indica and their cytotoxic activity against PANC-1 human pancreatic cancer cells
Fitoterapia, 121, 31-37 (2017).
DOI: 10.1016/j.fitote.2017.06.012
- Khang D.H. Nguyen, Phu H. Dang, Hai X. Nguyen, Mai T.T. Nguyen, Suresh Awale,* Nhan T. Nguyen*
Phytochemical and cytotoxic studies on the leaves of Calotropis gigantea
Bioorg. Med. Chem. Lett. 27, 2902-2906 (2017).
DOI: 10.1016/j.bmcl.2017.04.087
- Sivakalai Mayakrishnan, Yuvaraj Arun, Chandrasekar Balachandran, Suresh Awale, Narayanan Uma Maheswari, Paramasivan Thirumalai Perumal
Ru(II)-catalysed regiospecific C-H/O-H oxidative annulation to access isochromeno[8,1-ab]phenazines: far red fluorescence and live cancer cell imaging
ACS Omega, 2 (6), 2694–2705 (2017)
DOI: 10.1021/acsomega.7b00335
- Narayanasamy Sudhapriya, Chandrasekar Balachandran, Suresh Awale , Paramasivan Thirumalai Perumal
Sn(II)-mediated facile approach for the synthesis of 2-aryl-2H-indazole-3-phosphonates and their anticancer activity
New J. Chem., DOI:10.1039/C7NJ00843K (2017).
DOI: 10.1039/C7NJ00843K
- Awale S.,* Tawila A.M., Dibwe D.F., Ueda J, Sun S., Athikomkulchai S., Balachandran C., Saiki S., Matsumoto K., Esumi H.
Highly oxygenated antiausterity agents from the leaves of Uvaria dac
Bioorg. Med. Chem. Lett. 27(9 ), 1967-1971 (2017).
DOI: 10.1016/j.bmcl.2017.03.021
- Fujiwara H. , Han Y., Ebihara K., Awale S., Araki R., Yabe T. Matsumoto K.
Daily administration of yokukansan and keishito prevents social isolation-induced behavioral abnormalities and down-regulation of phosphorylation of neuroplasticity-related signaling molecules in mice
BMC Complement. Altern. Med. 17(1) · DOI: 10.1186/s12906-017-1710-7 (2017)
DOI: 10.1186/s12906-017-1710-7
- Balachandran C., Arun Y., Sangeetha B., Duraipandiyan V., Awale S., Emi N, Ignacimuthu S., Perumal P.T.
In vitro and in vivo anticancer activity of 2-acetyl-benzylamine isolated from Adhatoda vasica L. leaves .
Biomedicine & Pharmacotherapy , 93 , 796–806 (2017).
DOI: 10.1016/j.biopha.2017.06.096
- Dang P.H., Nguyen H.X., Duong T.T.T, Tran T.K.T., Nguyen P.T., Vu T.K.T, Vuong H.C, Phan T.H.N, Nguyen M.T.T, Nguyen N.T,* Awale S.*
α-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of Taxus wallichiana
J. Nat. Prod. , 80, 1087-1095 (2017).
DOI: 10.1021/acs.jnatprod.7b00006
- Nguyen N.T., Nguyen M.T.T., Nguyen H.X., Dang P.H., Dibwe D.F., Esumi H., Awale S.*
Constituents of the Rhizomes of Boesenbergia pandurata and Their Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Line
J. Nat. Prod. , 80, 141-148 (2017).
DOI: 10.1021/acs.jnatprod.6b00784
Year 2016
- Nguyen H.X., Do T.N.V, Le T.H., Nguyen M.T.T., Nguyen N.T., Esumi H., Awale S.
Chemical Constituents of Mangifera indica and Their Antiausterity Activity against the PANC‐1 Human Pancreatic Cancer Cell Line
J. Nat. Prod. , 79, 2053-2059 (2016).
- Nguyen H.X., Nguyen N.T., Dang P.H., Thi P.H., Nguyen M.T.T., Can M. V., Dibwe D.F., Ueda J., Awale S.
Cassane diterpenes from the seed kernels of Caesalpinia sappan.
Phytochemistry, 122, 286−293 (2016). - Farley C.M., Dibwe D.F., Ueda J., Hall E.A., Awale S., Magolan J.
Evaluation of Synthetic Coumarins for Antiausterity Cytotoxicity against Pancreatic Cancers.
Bioorg. Med. Chem. Lett. 26, 1471-1474 (2016). - Klionsky D.J. et al.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy, 12, 1-222 (2016). - Prangsaengtong O., Athikomkulchai S., Xu J., Koizumi K., Inujima A., Shibahara N., Shimada Y, Tadtong S., Awale S.
Chrysin Inhibits Lymphangiogenesis in Vitro
Biol. Pharm. Bull. 39, 466-472, (2016). - Nguyen H.X., Nguyen N.T., Dang P.H., Thi P.H., Nguyen M.T.T., Can M. V., Dibwe D.F., Ueda J., Matsumoto K., Awale S.
A New Cassane-type diterpene from the seed of Caesalpinia sappan.
Nat. Prod. Commun., 11, 723-724, (2016).
Year 2015
|
Year 2014
- Ueda J., Athikomkulchai S., Miyatake R., Saiki I, Esumi H., Awale S.
(+)-Grandifloracin, a novel Antiausterity Agent, Induces Autophagic PANC-1 Pancreatic Cancer Cell Death.
Drug Des. Dev. Ther. 8, 39−47 (2014).
- Nguyen M.T.T., Nguyen N.T., Nguyen K.D.H., Dau H.T.T., Nguyen H.X., Dang P.H., Le T.M., Phan T.H.N., Tran A.H., Nguyen B.D., Ueda J., Awale S.
Geranyl dihydrochalcones from Artocarpus altilis and their antiausteric activity.
Planta Med. 80, 193−200 (2014).
- Shakya B., Yadav P.N., Ueda J., Awale S.
Discovery of 2-pyridineformamide thiosemicarbazones as potent antiausterity agents.
Bioorg. Med. Chem. Lett. 24, 458−461 (2014).
- Awale S., Kato M., Dibwe D.F., Li F., Miyoshi C., Esumi H., Kadota S., Tezuka Y.
Antiausterity Activity of Arctigenin Enantiomers: Importance of (2R,3R)-Absolute Configuration.
Nat. Prod. Commun.9, 79−82 (2014).
- Dibwe D. F., Awale S., Kadota S., Morita H., Tezuka Y.
Muchimangins G–J, Fully Substituted Xanthones with a Diphenylmethyl Substituent, from Securidaca longepedunculata.
J. Nat. Prod., 77, 1241−1244 (2014).
- Dibwe D. F., Awale S., Kadota S., Morita H., Tezuka Y.
Two new diphenylmethyl-substituted xanthones from Securidaca longepedunculata.
Nat. Prod. Comm., 9, 655−657 (2014).
- Habibie, Yokoyama S., Abdelhamed S., Awale S., Sakurai H., Hayakawa Y., Saiki I.
Survivin suppression through STAT3/β-catenin is essential for resveratrol-induced melanoma apoptosis.
Int. J. Oncol. 45, 895−901 (2014).
- Abdelhamed S., Yokoyama S., Refaat A., Ogura K., Yagita H., Awale S., Saiki I.
Piperine Enhances the Efficacy of TRAIL-based Therapy for Triple-negative Breast Cancer Cells.
Anticancer Res. 34, 1893−1899 (2014).
- Dibwe D. F., Awale S., Kadota S., Morita H., Tezuka Y.
Muchimangins E and F: novel diphenylmethyl-substituted xanthones from Securidaca longepedunculata.
Tetrahedron Lett., 55, 1916−1919 (2014).
- Zhang H., Yamakawa Y., Matsuya Y., Toyooka N., Tohda C., Awale S., Li F., Kadota S, Tezuka Y.
Synthesis of long-chain fatty acid derivatives as a novel anti-Alzheimer's agent.
Bioorg. Med. Chem. Lett. 24, 604−608 (2014).
- Kato M., He Y., Dibwe D.F., Li F., Awale S., Kadota S., Tezuka Y.
New Guaian-type Sesquiterpene from Wikstroemia indica.
Nat. Prod. Commun. 9, 1−2 (2014).
Year 2013
[82] Dibwe D.F., Awale S., Kadota S., Morita H., Tezuka Y.
Heptaoxygenated xanthones as anti-austerity agents from Securidaca longepedunculata.
Bioorg. Med. Chem. 21, 7663−7668 (2013).
[81] Nguyen H.X., Nguyen M.T.T., Nguyen T.A., Nguyen N.Y.T., Phan D.A.T., Ho P.T., Phan T.H.N., Dang P.H., Nguyen N.T., Ueda J., Awale S.
Cleistanthane Diterpenes from the Seed of Caesalpinia sappan and their antiausteriy activity against PANC-1 human pancreatic cancer cell line.
Fitoterapia, 91, 148−153 (2013).
[80] Lirdprapamongkol K., Sakurai H., Abdelhamed S., Yokoyama S., Maruyama T., Athikomkulchai S., Viriyaroj A., Awale S., Yagita H., Ruchirawat S., Svasti J., Saiki I.
A flavonoid chrysin suppresses hypoxic survival and metastatic growth of mouse breast cancer cells.
Oncol. Rep. 30, 2357−2364 (2013).
[79] Athikomkulchai S., Awale S., Ruangrungsi N., Ruchirawat S., Kadota S.
Chemical Constituents of Thai propolis.
Fitoterapia, 88, 96−100 (2013).
[78] Lirdprapamongkol K., Sakurai H., Abdelhamed S., Yokoyama S., Athikomkulchai S., Viriyaroj A., Awale S., Ruchirawat S., Svasti J., Saiki I.
Chrysin overcomos TRAIL resistance of cancer cells though Mcl-1 down-regulation by inhibiting STAT3 phoshorylation.
Int. J. Oncol. 43, 329−337 (2013).
[77] Tezuka Y., Yamamoto K., Awale S., Feng L., Yomoda S., Kadota S.
Anti-austeric activity of phenolic constituents of seeds of Arctium lappa.
Nat. Prod. Commun. 8, 463−466 (2013).
[76] Abdelhamed S., Yokoyama S., Hafiyani L., Kalauni S.K., Hayakawa Y., Awale S., Saiki I.
Identification of plant extracts sensitizing breast cancer cells to TRAIL.
Oncol Rep., 29, 1991−1998 (2013).
[75] Kudou N., Taniguchi A., Sugimoto K., Matsuya Y., Kawasaki M., Toyooka N., Miyoshi C., Awale S., Dibwe D.F., Esumi H., KadotaS., Tezuka Y.
Synthesis and antitumor evaluation of arctigenin derivatives based on antiausterity strategy.
Eur. J. Med. Chem. 60, 76−88 (2013).
Heptaoxygenated xanthones as anti-austerity agents from Securidaca longepedunculata.
Bioorg. Med. Chem. 21, 7663−7668 (2013).
[81] Nguyen H.X., Nguyen M.T.T., Nguyen T.A., Nguyen N.Y.T., Phan D.A.T., Ho P.T., Phan T.H.N., Dang P.H., Nguyen N.T., Ueda J., Awale S.
Cleistanthane Diterpenes from the Seed of Caesalpinia sappan and their antiausteriy activity against PANC-1 human pancreatic cancer cell line.
Fitoterapia, 91, 148−153 (2013).
[80] Lirdprapamongkol K., Sakurai H., Abdelhamed S., Yokoyama S., Maruyama T., Athikomkulchai S., Viriyaroj A., Awale S., Yagita H., Ruchirawat S., Svasti J., Saiki I.
A flavonoid chrysin suppresses hypoxic survival and metastatic growth of mouse breast cancer cells.
Oncol. Rep. 30, 2357−2364 (2013).
[79] Athikomkulchai S., Awale S., Ruangrungsi N., Ruchirawat S., Kadota S.
Chemical Constituents of Thai propolis.
Fitoterapia, 88, 96−100 (2013).
[78] Lirdprapamongkol K., Sakurai H., Abdelhamed S., Yokoyama S., Athikomkulchai S., Viriyaroj A., Awale S., Ruchirawat S., Svasti J., Saiki I.
Chrysin overcomos TRAIL resistance of cancer cells though Mcl-1 down-regulation by inhibiting STAT3 phoshorylation.
Int. J. Oncol. 43, 329−337 (2013).
[77] Tezuka Y., Yamamoto K., Awale S., Feng L., Yomoda S., Kadota S.
Anti-austeric activity of phenolic constituents of seeds of Arctium lappa.
Nat. Prod. Commun. 8, 463−466 (2013).
[76] Abdelhamed S., Yokoyama S., Hafiyani L., Kalauni S.K., Hayakawa Y., Awale S., Saiki I.
Identification of plant extracts sensitizing breast cancer cells to TRAIL.
Oncol Rep., 29, 1991−1998 (2013).
[75] Kudou N., Taniguchi A., Sugimoto K., Matsuya Y., Kawasaki M., Toyooka N., Miyoshi C., Awale S., Dibwe D.F., Esumi H., KadotaS., Tezuka Y.
Synthesis and antitumor evaluation of arctigenin derivatives based on antiausterity strategy.
Eur. J. Med. Chem. 60, 76−88 (2013).
Year 2012
- Awale S., Ueda J., Athikomkulchai S., Abdelhamed S., Yokoyama S., Saiki I., Miyatake R.
Antiausterity Agents from Uvaria dac and Their Preferential Cytotoxic Activity against Human Pancreatic Cancer Cell Lines in a Nutrient-Deprived Condition.
J. Nat. Prod. 75, 1177−1183 (2012).
- Awale S., Ueda J., Athikomkulchai S., Dibwe D.F., Abdelhamed S., Yokoyama S., Saiki I., Miyatake R.
Uvaridacols E-H, Highly Oxygenated Antiausterity Agents from Uvaria dac.
J. Nat. Prod.75, 1999−2002 (2012).
- Dibwe D.F., Awale S., Kadota S. Tezuka Y.
Muchimangins A–D: novel diphenylmethyl-substituted xanthones from Securidaca longepedunculata.
Tetrahedron Lett. 53, 6186−6190 (2012).
- Li F., Okamura Y.,Dibwe D. F., Awale S., Kadota S., Tezuka Y.
Anti-Austerity Agents from Rhizoma et Radix Notopterygii (Qianghuo).
Planta Med. 78, 796−799 (2012).
- Dibwe D. F., Awale S., Kadota S., Tezuka Y.
Damnacanthal from the Congolese Medicinal Plant Garcinia huillensis has a Potent Preferential Cytotoxicity against Human Pancreatic Cancer PANC-1 Cells.
Phytother. Res. 25, 1920-1926 (2012).
Year 2011
- Awale S., Linn TZ., Feng L., Tezuka Y., Myint A., Tomida A., Yamori T., Esumi H., Kadota S.
Identification of Chrysoplenetin from Vitex negundo as a Potential Cytotoxic Agent against PANC-1 and a Panel of 39 Human Cancer Cell Lines (JFCR-39).
Phytother. Res. 25, 1770−1775 (2011).
- Devji T., Reddy C., Woo C., Awale S., Kadota S., Carrico-Moniz D.
Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivative.
Bioorg. Med. Chem. Lett. 21, 5770−5773 (2011).
- Li F., He Y., Awale S., Kadota S., Tezuka Y.
Two new cytotoxic phenylallylflavanones from mexican propolis.
Chem. Pharm. Bull. 59, 1194−1196 (2011).
- Tezuka Y., Morikawa K., Li F., Auw L., Awale S., Nobukawa T., Kadota S.
Cytochrome P450 3A4 Inhibitory Constituents of the Bark of Taxus yunnanensis.
J. Nat. Prod. 74, 102−105 (2011).
- Kharel P., Manandhar M.D., Kalauni S. K., Awale S., Baral J.
Isolation, identification and antimicrobial activity of withanolide WS-1 from roots of Withania somnifera.
Nep. J. Sci. Tech. 12, 179-186 (2011).
- Dhakal R. C., Kalauni S. K., Awale S., Shrestha K., and Gewali M. B.
Isolation and characterization of sterols and an aliphatic alcohol from Tsuga dumosa D. Don of Nepal.
Scientific World 9, 16−17 (2011).
- Thapaliya E. R., Kalauni S. K., Awale S., Adhikari A., Chaudhary M. I., and Mahandhar M. D.
Isolation and characterization of neoflavonoid and a fatty acids from propolis of Apis mellifera of Nepal.
J. Alp. Chem. 2, 24−29 (2011).
Year 2000-2010
- Feng L., Awale S., Tezuka Y., Kadota S.
Cytotoxicity of Constituents from Mexican Propolis Against a Panel of Six Different Cancer Cell Lines.
Nat. Prod. Commun. 5, 1601−1606 (2010).
- Widyowati R., Tezuka Y., Miyahara T., Awale S., Kadota S.
Alkaline Phosphatase (ALP) Enhancing Iridoid Glucosides from the Indonesian Medicinal Plant Barleria lupulina.
Nat. Prod. Commun. 5, 1711−1716 (2010).
- Morikawa K., Tanaka K., Li F., Awale S., Tezuka Y., Nobukawa T., Kadota S.
Analysis of MS/MS fragmentation of taxoids.
Nat. Prod. Commun. 5, 1551−1556 (2010).
- Luitel H.N., Rajbhandari M., Kalauni S.K., Awale S., Masuda K., Gewali M.B.
Chemical Constituents from Oroxylum indicum (L.) Kurz of Nepalese Origin.
Scientific World 8, 66−68, (2010).
- Miyake K., Feng L., Tezuka Y., Awale S., and Kadota S.
Cytotoxic Activity of Quasinnoids from Eurycoma longifolia.
Nat. Prod. Commun. 5, 1009−1012 (2010).
- Feng L., Awale S., Tezuka Y., Esumi H., Kadota S.
Study on the Constituents of Mexican Propolis and their Cytotoxic Activity Against PANC-1 Human Pancreatic Cancer Cells.
J. Nat. Prod. 73, 623−627 (2010).
- Miyake K., Tezuka Y., Awale S., Feng L., Kadota S.
Canthin-6-one Alkaloids and a Tirucallanoid from Eurycoma longifolia Jack and Their Cytotoxic Activity against Human HT-1080 Fibrosarcoma Cell Line.
Nat. Prod. Commun. 5, 17−22 (2010).
- Awale S., Miyamoto T., Linn T.Z., Feng L., Win N.N., Tezuka Y., Esumi H., Kadota S.
Cytotoxic constituents Soymida febrifuga from Myanmar.
J. Nat. Prod. 72, 1631−1636 (2009).
- Miyake K., Tezuka Y., Awale S., Feng L., Kadota S.
Quassinoids from Eurycoma longifolia Jack .
J. Nat. Prod. 72, 2135−2140 (2009).
- Feng L., Awale S., Tezuka Y.,, Kadota S.
Cytotoxic activity of the constituents of propolis from Myanmar against a panel of six cancer cell line and their structure-activity relationship.
Biol. Pharm. Bull. 32, 2075−2078, (2009).
- Dhakal R., Rajbhandari M., Kalauni S.K., Awale S., Gewali M.B.
Phytochemical constituents of the bark of Vitex negundo L.
J. Nep. Chem. Soc. 23, 89−92 (2009).
- Feng L., Awale S., Zhang H., Tezuka Y., Esumi H., Kadota S.
Chemical Constituents of Propolis from Myanmar and Their Preferential Cytotoxicity against a PANC-1 Human Pancreatic Cancer Cell Line.
J. Nat. Prod. 72, 1283−1287 (2009).
- Awale S., Feng L., Onozuka H., Esumi H., Tezuka Y., Kadota S.
Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line under nutrient deprived condition.
Bioorg. Med. Chem. 16, 181−189 (2008).
- Awale S., Hamazaki T., Kadowaki M., Saiki I., Tezuka Y., Kadota S.
Commonly Encountered Diseases in Traditional Medicine in “Myanmar Traditional Medicine Handbook“ Published by Department of Traditional Medicine, Ministry of Health and Japan International Cooperation Agency (JICA), 89-120, 2008.
- Win N.N., Awale S., Esumi H., Tezuka Y., Kadota S.
Novel Anticancer Agents, Kayeassamins C-I from the Flower of Kayea assamica of Myanmar.
Bioorg. Med. Chem. 16, 8653−8660 (2008).
- Win N.N., Awale S., Esumi H., Tezuka Y., Kadota S.
Novel anticancer agents, kayeassamins A and B from the flower of Kayea assamica of Myanmar.
Bioorg. Med. Chem. Lett. 18, 4688−4691 (2008).
- Feng L., Awale S., Tezuka Y., Kadota S.
Cytotoxic constituents from Brazilian red propolis and their structure–activity relationship.
Bioorg. Med. Chem. 16, 5434−5440 (2008).
- Win N. N., Awale S., Esumi H., Tezuka Y., Kadota S.
Panduratins D−I, Novel Secondary Metabolites from Rhizomes of Boesenbergia pandurata.
Chem. Pharm. Bull. 56, 491−496 (2008).
- Win N. N., Awale S., Esumi H., Tezuka Y., Kadota S.
Bioactive Secondary Metabolities from Boesenbergia pandurata of Myanmar and Their Preferential Cytotoxicity Against Human Pancreatic Cancer PANC-1 Cell Line Under Nutrient Deprived Condition.
J. Nat. Prod. 70, 1582−1587 (2007).
- Mangestuti, Subehan, Widyawaruyanti A., Zaidi S. F. H., Awale S., Kadota S.
Traditional medicine of Madura Island in Indonesia.
J. Trad. Med. 24, 90−103 (2007).
- Widyawaruyanti A., Subehan, Kalauni S. K., Awale S., Nindatu M., Zaini N. C., Syafruddin D., Asih P. B. S., Tezuka Y., Kadota S.
New Prenylated Flavones from Atrocarpus champeden and their Antimalarial activity in vitro.
J. Nat. Med. 61, 410−413 (2007).
- Awale S., Linn T.Z., Than M.M., Thet M. M., Swe T., Saiki I., Kadota S.
An amazing cow’s urine therapy practice in Myanmar.
J. Trad. Med. 23, 178−183 (2006).
- Awale S., Lu J., Kalauni S. K., Kurashima Y., Tezuka Y., Kadota S., Esumi H.
Identification of arctigenin as an Anti-tumor Agent having activity to Eliminate Cancer Cell’s Tolerance to Nutrient Starvation.
Cancer Res. 66, 1751−1753 (2006).
- Awale S., Nakashima E. M. N., Kalauni S. K., Tezuka Y., Lu J., Kurashima Y., Esumi H., Kadota S.
Angelmarin, a Novel Anticancer Agent Able to Eliminate the Tolerance of Cancer Cells to Nutrition Starvation.
Bioorg. Med. Chem. Lett. 16, 581−583 (2006).56.
- Awale S., Linn T.Z., Than M.M., Saiki I., Kadota S.
The Healing Art of Traditional Medicines in Myanmar.
J. Trad. Med. 23, 47−68 (2006).
- Awale S., Linn T.Z., Tezuka Y., Banskota A.H., Kalauni S.K., Attamimi F., Ueda J., Kadota S.
Constituents of Caesalpinia crista from Indonesia.
Chem. Pharm. Bull. 54, 213−218 (2006).
- Ueda J., Awale S., Tezuka Y., Shimamura E., Hirai K., Nobukawa T., Kadota S.
Growth Inhibitory Activity of Wood of Taxus yunnanensis and its Liquid Chromatography Fourier-Transform Mass Spectrometry Analysis.
Planta Med. 72, 1241−1244 (2006).
- Zaidi S. F. H., Awale S., Kalauni S. K., Tezuka Y., Esumi H., Kadota S.
Diterpenes from Pini Resina and Their Preferential Cytotoxic Activity under Nutrient-Deprived Condition.
Planta Med. 72, 1231−1234, (2006).
- Nguyen M. T., Tran Q.L., Nakashima E. M. N., Awale S., Kadota S.
Investigation on traditional medicine at Phu uoc Island and Ninh Thuan Province in Vietnam.
J. Trad. Med. 23, 69−82 (2006).
- Kalauni S.K., Awale S., Tezuka Y., Banskota A.H., Linn T.Z., Asih P.B.S., Syafruddin D., Kadota S.
Antimalarial Activity of Cassane- and Norcassane-type Diterpenes from Caesalpinia Crista and Their Structure-Activity Relationship.
Biol. Pharm. Bull. 29, 1050−1052 (2006).
- Awale S., Kawakami T., Tezuka Y., Ueda J., Tanaka K., Kadota S.
Nitric Oxide (NO) Production Inhibitory Constituents of Tabebuia avellanedae from Brazil.
Chem. Pharm. Bull. 53, 710−713 (2005).
- Awale S., Shrestha S. P., Tezuka Y., Ueda J., Matsushige K., Kadota S.
Flavanoids from Nepalese Propolis and Their Nitric Oxide Production Inhibitory Activity.
J. Nat. Prod. 68, 858−864 (2005).
- Nguyen M. T., Awale S., Tezuka Y., Ueda J., Tran Q.L., Kadota S.
Xanthine Oxidase Inhibitors from the Flowers of Chrysanthemum sinense.
Planta med. 72, 46−51 (2006).
- Toyooka N., Kawasaki M., Nemoto H., Awale S., Tezuka Y., Kadota S.
Synthetic studies on the poison-frog alkaloid 261C.
Synlett. 20, 3109−3110 (2005).
- Nguyen M. T., Awale S., Tezuka Y., Shi L., Zaidi S. F. H., Ueda J., Tran Q.L., Murakami Y., Matsumoto K., Kadota S.
Hypouricemic Effects of Acacetin and 4,5-O-Dicaffeoylquinic Acid Methyl Ester on Serum Uric Acid Levels in Potassium Oxonate-Pretreated Rats.
Biol. Pharm. Bull. 28, 2231−2234 (2005).
- Kalauni S.K., Awale S., Tezuka Y., Banskota A.H., Linn T.Z., Kadota S.
Methyl Migrated Cassane-Type Furanoditerpenes of Caesalpinia crista from Myanmar.
Chem. Pharm. Bull. 53, 1300−1304 (2005).
- Nguyen M. T., Awale S., Tezuka Y., Tran Q.L., Kadota S.
Xanthine Oxidase Inhibitors from the Heartwood of Vietnamese Caesalpinia sappan.
Chem. Pharm. Bull. 53, 984-988 (2005).
- Kalauni S.K., Awale S., Tezuka Y., Banskota A.H., Linn T.Z., Kadota S.
New Cassane-type Diterpenes of Caesalpinia crista from Myanmar.
Chem. Pharm. Bull. 53, 214−218 (2005).
- Linn T.Z., Awale S., Tezuka Y., Banskota A.H., Kalauni S.K., Attamimi F., Ueda J., Asih P.B.S., Syafruddin D., Tanaka K., Kadota S.
New Cassane- and Norcassane-type Diterpenes from Caesalpinia crista of Indonesia and Their Antimalarial Activity against the Growth of Plasmodium falciparum.
J. Nat. Prod. 68, 706−710 (2005).
- Gautam L. N., Awale S., Kalauni S. K., Shrestha S. and Gewali, M. B.
Phytochemical and Biological Studies on Podocarpus nerifolius D. Don, A Himalayan Conifer of Nepal.
Scientific World, 3, 22−25 (2005).
- Awale S., Tezuka Y., Kobayashi M., Ueda J., Kadota S.
Neoorthosiphonone A, a Nitric oxide (NO) Inhibitory Diterpene with a New Carbon Skeleton from Orthosiphon stamineus.
Tetrahedron Lett. 45, 1359−1362 (2004).
- Kalauni S.K., Awale S., Tezuka Y., Banskota A.H., Linn T.Z., Kadota S.
Cassane- and Norcassane-type Diterpenes from Caesalpinia crista from Myanmar.
J. Nat. Prod. 67, 1859−1863 (2004).
- Nguyen M. T., Awale S., Tezuka Y., Tran Q.L., Kadota S. Neosappanone A, a Xanthine Oxidase (XO) Inhibitory Dimeric Methanodibenzoxocinone with a New Carbon Skeleton from Caesalpinia sappan.
Tetrahedron Lett. 45, 8519−8522 (2004).
- Nguyen M. T., Awale S., Tezuka Y., Tran Q.L., Watanabe H., Kadota S.
Xanthine Oxidase Inhibitory Activity of Vietnamese Medicinal Plants.
Biol. Pharm. Bull. 27, 1414−1421 (2004).
- Nguyen M. T., Awale S., Tezuka Y., Chien-Hsiung C., Kadota S.
Staminane- and Isopimarane-type Diterpenes from Orthosiphon stamineus of Taiwan and Their Nitric Oxide Inhibitory Activity.
J. Nat. Prod. 67, 654−658 (2004).
- Awale S., Tezuka Y., Banskota A. H., Kadota S.
Siphonols A-E, Novel Potent Nitric Oxide Inhibitors From Orthosiphon Stamineus of Indonesia.
Bioorg. Med. Chem. Lett. 13, 31−35 (2003).
- Awale S., Tezuka Y., Banskota A. H., Adnyana I. K., Kadota S.
Nitric Oxide Inhibitory Isopimarane-type Diterpenes from Orthosiphon stamineus of Indonesia.
J. Nat. Prod. 55, 2755−2758 (2003).
- Awale S., Tezuka Y., Banskota A. H., Kadota S.
Inhibition of Nitric Oxide Production by Highly-Oxygenated Diterpenes of Orthosiphon stamineus and their Structure-Activity Relationship.
Bio. Pharm. Bull. 26, 468−473 (2003).
- Awale S., Tezuka Y., Banskota A. H., Adnyana I. K., Kadota S.
Highly-Oxygenated Isopimarane-type Diterpenes from Orthosiphon stamineus of Indonesia and their Nitric Oxide Inhibitory Activity.
Chem. Pharm. Bull. 51, 268−275 (2003).
- Awale S., Wang S., Tezuka Y., Banskota A. H., Tran K. Q., Kadota S.
Antioxidative and Antihepatotoxic Principles of Toucha.
J. Trad. Med. 20, 45−50 (2003).
- Banskota A. H., Tezuka Y., Nguyen N. T., Awale S., Nobukawa T., Kadota S.
DPPH Radical Scavenging and Nitric Oxide Inhibitory Activities of the Constituents from the Wood of Taxus yunnanensis.
Planta Med. 69, 500−505 (2003).
- Awale S., Tezuka Y., Wang S., Kadota S.
Facile and Regioselective Synthesis of Phenylpropanoid-substituted Flavan-3-ols.
Org. Lett. 4, 1707−1709 (2002).
- Awale S., Tezuka Y., Banskota A. H., Shimoji S., Taira K., Kadota S.
Norstaminane- and Isopimarane-type Diterpenes of Orthosiphon stamineus From Okinawa.
Tetrahedron 58, 5503−5512 (2002).
- Awale S., Tezuka Y., Shimoji S., Taira K., Kadota S.
Secoorthosiphols A-C; Three Highly Oxygenated Secoisopimarane-type Diterpenes From Orthosiphon Stamineus.
Tetrahedron Lett. 43, 1473−1475 (2002).
- Awale S., Tezuka Y., Banskota A. H., Kouda K., Tun K. M., Kadota S.
Four Highly Oxygenated Isopimarane-type Diterpenes of Orthosiphon stamineus.
Planta Med. 68, 286−288, 2002.
- Banskota A. H., Nagaoka T., Sumioka L. Y., Tezuka Y., Awale S., Midorikawa K., Matsushige K., Kadota S.
Antiproliferative activity of the Netherlands propolis and its active principles in cancer cell lines.
J. Ethnopharmacol. 80, 67−73 (2002).
- Awale S., Tezuka Y., Banskota A. H., Kouda K., Tun K. M., Kadota S.
Five Novel Highly Oxygenated Diterpenes of Orthosiphon stamineus from Myanmar.
J. Nat. Prod. 64, 592−596 (2001).
- Ali M. S., Tezuka Y., Awale S., Banskota A. H., Kadota S.
Six New Diarylheptanoids from the Seeds of Alpinia blepharocalyx.
J. Nat. Prod. 64, 289−293 (2001).
- Adnyana I K., Tezuka Y., Awale S., Banskota A. H., Tran K. Q., Kadota S.
1-O-Galloyl-6-O-(4-hydroxy-3,5-dimethoxy)benzoyl-b-D-glucose, a new hepatoprotective constituent from Combretum quadrangulare.
Planta Med. 67, 370−371 (2001).
- Tezuka Y., Stampoulis P., Banskota A. H., Awale S., Tran K. Q., Saiki I., Kadota S.
Constituents of Vietnamese medicinal plant Orthosiphon stamineus.
Chem. Pharm. Bull. 48, 1711−1719 (2000). - Adnyana I K., Tezuka Y., Awale S., Banskota A. H., Tran K. Q., Kadota S.
Quadranosides VI-XI, six new triterpene glucosides from the seeds of Combretum quadrangulare.
Chem. Pharm. Bull. 48, 1114−1120 (2000).